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Avaliação do uso tópico da ALOE vera no reparo tecidual de feridas crônicas

2026-02-24T12:28:56Z

Título: Avaliação do uso tópico da ALOE vera no reparo tecidual de feridas crônicas Autor: PEREIRA, Girlane Caroline Primeiro orientador: DIAS, Rosilda Silva Abstract: Introduction: The management of chronic wounds represents a persistent challenge in healthcare services, requiring therapeutic alternatives that are effective, safe, and accessible. Aloe vera (L.) Burm. f. stands out in phytotherapy due to its anti- inflammatory, antioxidant, and regenerative properties, being considered a promising option in the wound healing process. Objective: To evaluate the clinical and histological effects of the topical application of in natura Aloe vero gel on the tissue repair of chronic wounds of different etiologies. Methods: This is a descriptive, quantitative, longitudinal case series clinical study conducted from August to October 2025 in a specialized outpatient clinic for the care of people with chronic wounds, linked to a public hospital in the municipality of São Luís, Maranhão, Brazil. Follow-up included serial clinical evaluations and comparative histological analysis at baseline (Day 0) and at the end (Day 15), aiming to analyze tissue and cellular evolution. Results: Favorable clinical evolution was observed in all participants, characterized by reduction of exudate, improvement in wound bed appearance, progression of epithelialization, and decreased pain intensity. In three participants, complete formation of granulation tissue was observed at the end of the follow-up period. Histological analysis corroborated the clinical findings, showing reduced inflammatory infiltrate, increased angiogenesis, and proliferation of young fibroblasts, consistent with progression to the proliferative phase of tissue repair. Conclusion: The topical use of in natura Aloe vera gel demonstrated positive effects on tissue repair and pain control in chronic wounds, representing a safe, low-cost, and potentially relevant therapeutic alternative for nursing practice. The findings indicate the feasibility of incorporating this approach as a complementary strategy in the care of chronic wounds within the Unified Health System (SUS). Instituição: Universidade Federal do Maranhão Tipo do documento: Dissertação

Avaliação da sepse em terapia intensiva: análise dos dados clínico-laboratoriais e diagnósticos de enfermagem NANDA Internacional

2026-02-20T14:25:24Z

Título: Avaliação da sepse em terapia intensiva: análise dos dados clínico-laboratoriais e diagnósticos de enfermagem NANDA Internacional Autor: CARVALHO, Wildilene Leite Primeiro orientador: SILVA, Andréa Cristina Oliveira Abstract: Sepsis remains one of the major challenges in Intensive Care Units, characterized by high morbidity and mortality and complex care demands. This study aimed to analyze clinical and laboratory data and NANDA-I nursing diagnoses recorded in the medical records of patients diagnosed with sepsis and septic shock in an adult Intensive Care Unit. This was a documentary, analytical, and retrospective study with a quantitative approach, conducted using medical records of patients admitted between 2022 and 2024 and approved by the Research Ethics Committee under protocol number 7,589,331. A total of 78 medical records were analyzed. The results showed a predominance of female patients and older adults (age range: 20 to 83 years), as well as significant hemodynamic instability, with frequent need for mechanical ventilation, vasopressor therapy, and invasive devices. The main infectious foci were ventilator- associated pneumonia and catheter-associated bloodstream infection. Microbiological analysis revealed a predominance of multidrug-resistant Gram-negative bacilli, including Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter baumannii, in addition to a relevant presence of Candida species. Antimicrobial therapy predominantly involved broad-spectrum agents, reflecting the resistance profile identified. The most frequent nursing diagnoses were Risk for Infection, Risk for Pressure Injury in Adults, Impaired Spontaneous Ventilation, and Impaired Self-Care Syndrome. After applying the False Discovery Rate adjustment, fourteen associations between nursing diagnoses and categorical variables remained statistically significant. Among continuous variables, a strong correlation was observed between urea and creatinine levels, and a moderate correlation between SOFA score and creatinine. For the nursing diagnosis Risk for Infection – Invasive Procedure, elevated bilirubin levels and the presence of septic shock were identified as strong predictors. Receiver operating characteristic curve analysis demonstrated that this diagnosis showed the highest accuracy among the tested models, indicating its potential as a useful predictive tool in clinical practice. It is concluded that sepsis in intensive care settings presents an etiology predominantly associated with the hospital environment and requires integrated action by the multidisciplinary team. The findings reinforce the strategic role of nurses in the Nursing Process, particularly in clinical surveillance, early risk identification, and diagnostic accuracy. Overall, the results highlight that certain nursing diagnoses have relevant predictive value, standing out as clinical judgments capable of anticipating clinical deterioration and supporting decision-making in patients with sepsis. Instituição: Universidade Federal do Maranhão Tipo do documento: Dissertação

Qualidade de vida de pessoas idosas negras com hipertensão arterial

2026-02-11T12:22:26Z

Título: Qualidade de vida de pessoas idosas negras com hipertensão arterial Autor: SILVA, Eusiene Furtado Mota Primeiro orientador: SARDINHA, Ana Hélia de Lima Abstract: Systemic arterial hypertension is one of the most prevalent chronic conditions among older adults and affects the Black population more significantly, compromising their quality of life. The intersection between race, aging, and chronic conditions highlights historical inequities in access to healthcare and living conditions, reinforcing the importance of assessing the quality of life of this population to support equitable public policies and culturally sensitive care practices. The objective of this study was to evaluate the quality of life of older Black people with hypertension. This is a cross- sectional and analytical study, conducted between January and June 2025. Data collection was conducted in person by the principal investigator, using two structured questionnaires: the first addressing sociodemographic variables, lifestyle habits, clinical aspects, and anthropometric data; and the second corresponding to the validated Medical Outcomes Short-Form Health Survey (SF-36), which assesses eight domains of quality of life. Data analysis was performed using the Statistical Package for the Social Sciences (version 24.0), employing the Mann-Whitney, Kruskal-Wallis, and Spearman correlation tests (p < 0.05). The sample consisted of 191 individuals, predominantly women (65.4%), with a median age of 72 years, married (70.2%), retired (89.0%), and with an income between one and three minimum wages (93.2%), as well as having incomplete primary education (41.9%). The majority did not smoke (92.7%), did not consume alcohol (90.1%), and only 37.7% practiced physical activity. Regarding clinical aspects, 89% had lived with the diagnosis for more than six years, and 99.0% were undergoing drug treatment. The median Body Mass Index was 26 kg/m2, and the median waist circumference was 92.8 cm. The lowest quality of life scores were observed in the domains of pain (median=32), emotional aspects (median=33.3), and vitality (median=40), while mental health (median=72) and social aspects (median=50) showed better values. Participants with higher education levels, those who practiced physical activity, and single individuals presented higher scores (p < 0.001). Longer time since diagnosis, smoking, and low levels of physical activity were associated with worse results in multiple domains (p<0.05). The presence of other chronic conditions was associated with higher scores in the domains of vitality, pain, emotional aspects, social aspects, and mental health (p < 0.05). The use of private services and regular attendance at services also showed positive associations with several domains. It is concluded that sociodemographic, clinical, and behavioral factors influence the quality of life of elderly Black people with systemic arterial hypertension. The predominance of women with low levels of education and income, coupled with overweight, sedentary lifestyles, and comorbidities, creates a vulnerable scenario that particularly compromises the domains of pain, emotional well-being, and vitality, reinforcing the need for culturally sensitive and equitable care strategies in primary health care. Instituição: Universidade Federal do Maranhão Tipo do documento: Dissertação

FENOMENOLOGIA DA PERDA E DO CUIDADO DE ENFERMAGEM: O SER FAMILIAR DIANTE DO ADOECIMENTO E MORTE POR COVID-19

2026-01-22T17:23:53Z

Título: FENOMENOLOGIA DA PERDA E DO CUIDADO DE ENFERMAGEM: O SER FAMILIAR DIANTE DO ADOECIMENTO E MORTE POR COVID-19 Autor: ANDRADE, Thátila Larissa da Cruz Primeiro orientador: SILVA, Líscia Divana Carvalho Abstract: In the context of the covid-19 pandemic, nursing care played a significant role, requiring an even deeper ontological understanding that permeated the daily relationship between the caregiver-the nurse-and the one who experienced it profoundly-the family. Illness and loss due to covid-19 altered family dynamics with mutual influences in a scenario full of uncertainties, directly impacting the experience of grief. Thus, it is understood that the suffering in the face of loss and the nursing care received reshaped the way of living.The study aimed to understand the meaning of the loss of a loved one and of nursing care for the family-being in the context of illness and death due to covid-19 in a hospital setting. This is a qualitative, phenomenological study, having Martin Heidegger’s Being and Time as its philosophical theoretical framework and hermeneutic analysis as its methodological reference, which is dedicated to presenting the meaning of the existentiality of “Being”. Physical medical records of patients who died from covid-19 in a public hospital located in the Central-North region of São Luís, Maranhão, were identified. Ten (10) nuclear family and extended family members of patients who accompanied their loved one's illness and death from covid-19 participated in the research, residing in São Luís, aged 18 years or older, both sexes and who consentend by signing a form. The research was conducted at the family members’ homes from August to December 2024, in São Luís, Maranhão. The understanding and interpretation of data were based on Martin Heidegger’s hermeneutic circle. Three (3) units of meaning and signification were identified: “The family-being in the face of a loved one’s illness”; “The family-being in the face of a loved one’s death”; “The nursing-being for the family member.” The family-being, in the face of their loved one’s illness, shares a network of affection, care, and responsibilities, becoming immersed in the perplexity of life’s vulnerability.This experience provokes a reconfiguration of daily life, experiencing the distancing imposed by sanitary measures, destabilizing pre-existing certainties, and requiring adaptation to the new, which becomes strained by uncertainty, sadness, and fear-circumstances that bring the family-being closer to existential anguish.The family-being in the face of the death of their loved one is permeated by the expectation of recovery and does not recognize the possibility of life’s finitude, which generates helplessness and anguish, culminating in sadness and guilt. This irreversible rupture with their loved one, in the face of powerlessness and inevitability, highlights the emotional impact of loss, loneliness, and the grieving process, leading to a reorganization of the family system in search of a new balance. Nursing care, beyond the technical dimension, manifested as a sensitive, empathetic, and supportive presence, contributing to this re-signification, especially in a context of isolation and absence of farewells. The nursing practice was recognized as an expression of ontological care, which embraces human vulnerability and finitude, manifested through attentive listening and the ethics of care. It is concluded that the loss of a loved one faced by family members was marked by profound anguish, sadness, guilt, helplessness, and loneliness. The pandemic imposed unprecedented challenges to the existential dimension of nursing care for families, highlighting the need for a deep understanding of the uniqueness of experiences, valuing encounters with life’s finitude, vulnerabilities, and the deepest needs of the being, contributing to a more empathetic, dignified, and compassionate being-with relationship. The optical-phenomenological-reflective essay of this research contributes to the ingenious dialogical process also with other philosophers in uncovering and revealing to understand the true self, subsidizing more sensitive, ethical and authentic practices, contributing to the resignification of grief, existence, suffering and death. Instituição: Universidade Federal do Maranhão Tipo do documento: Dissertação